Effects of ergotamine on cardiovascular catecholamine receptors in the pithed rat.

@article{Bada1988EffectsOE,
  title={Effects of ergotamine on cardiovascular catecholamine receptors in the pithed rat.},
  author={A. Bernat Bad{\'i}a and A. Mor{\'o}n and L Cuff{\'i} and Elisabet Vila},
  journal={General pharmacology},
  year={1988},
  volume={19 3},
  pages={475-81}
}
1. Ergotamine (3-10 micrograms/kg) inhibited the electrical stimulation-induced pressor and cardiac responses without modifying pressor responses of noradrenaline and tyramine in the pithed rat. 2. Yohimbine (0.3 mg/kg) partially prevented the ergotamine cardiac and vascular inhibitory effects but sulpiride (0.3 mg/kg) only prevented it at vascular level. Both antagonists together abolished the ergotamine inhibition of electrical stimulation-induced pressor responses. 3. The cumulative dose… CONTINUE READING