Effects of equal weight loss with orlistat and placebo on body fat and serum fatty acid composition and insulin resistance in obese women.

@article{Tiikkainen2004EffectsOE,
  title={Effects of equal weight loss with orlistat and placebo on body fat and serum fatty acid composition and insulin resistance in obese women.},
  author={Mirja Tiikkainen and Robert Bergholm and Aila M. Rissanen and Antti Aro and Irma Salminen and Marjo Tamminen and Kari Teramo and Hannele Yki-J{\"a}rvinen},
  journal={The American journal of clinical nutrition},
  year={2004},
  volume={79 1},
  pages={22-30}
}
BACKGROUND Dietary fat has been reported to influence insulin sensitivity. OBJECTIVE The objective of the study was to determine how identical weight loss (target: loss of 8% of body weight over 3-6 mo) in women taking orlistat or placebo combined with a hypocaloric diet influences body composition and insulin sensitivity. DESIGN Forty-seven obese women [body mass index (in kg/m(2)): 32.1 +/- 0.4] were randomly assigned to receive either orlistat (120 mg 3 times daily; n = 23) or placebo (n… CONTINUE READING

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