Effects of epidermal growth factor on apo B mRNA levels and apo B accumulation in the media of primate hepatocytes in culture.

@article{Blake1992EffectsOE,
  title={Effects of epidermal growth factor on apo B mRNA levels and apo B accumulation in the media of primate hepatocytes in culture.},
  author={William L Blake and Thomas J. Vidmar and George W. Melchior},
  journal={Biochemical and biophysical research communications},
  year={1992},
  volume={186 1},
  pages={199-204}
}
EGF has been shown to augment albumin and apolipoprotein A-I secretion by cynomolgus monkey hepatocytes in primary culture without stimulating cell division. This study was undertaken to determine what effect EGF had on apo B secretion by those hepatocytes. The results indicate that EGF (3 nM final concentration) severely inhibits the rate at which apo B… CONTINUE READING