Effects of environmental stress on tissue survival and neutrophil recruitment in surgical skin flaps in relation to plasma corticosterone levels in the rat

Abstract

Objective: Because glucocorticoid treatment can improve the survival of surgical skin flaps, we examined the influence of environmental stress on skin flap survival in the rat.¶Material: Female Sprague-Dawley rats.¶Treatment: Dexamethasone (1 mg/kg i.p.).¶Methods: A standardized dorsal skin flap was raised and sutured back into position, and six days later… (More)
DOI: 10.1007/s000110050173

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