Effects of enhanced activity on synaptic transmission in mouse extensor digitorum longus muscle.

@article{Dorlchter1991EffectsOE,
  title={Effects of enhanced activity on synaptic transmission in mouse extensor digitorum longus muscle.},
  author={Marlies Dorl{\"o}chter and Andrey Irintchev and Martijn Brinkers and Anton Wernig},
  journal={The Journal of physiology},
  year={1991},
  volume={436},
  pages={283-92}
}
1. Transmitter release at neuromuscular junctions of extensor digitorum longus (EDL) muscle in mice was studied after 2-8 month periods of unforced running in wheels. 2. Intracellular recordings at 10 Hz stimulation revealed that the quantal content of endplate potentials (EPPs) in Mg(2+)-blocked preparations was larger by 30% in trained (mean number of quanta, m = 1.75 +/- 0.19, n = 7) than in untrained control EDL muscles (m = 1.35 +/- 0.35, n = 7). Similarly the amplitudes of the first… CONTINUE READING

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