Effects of endotoxin on lung pericytes in vitro.

  title={Effects of endotoxin on lung pericytes in vitro.},
  author={Joseph E.L. Khoury and David Langleben},
  journal={Microvascular research},
  volume={56 2},
Lipopolysaccharide released during bacterial sepsis causes acute lung injury and ARDS. Pulmonary microvascular injury is a feature of ARDS, and vascular remodeling develops, leading to pulmonary hypertension. Pericytes in the lung circulation proliferate and contribute to the remodeling seen in experimental sepsis. It is unknown whether endotoxin can… CONTINUE READING