Effects of endomorphin-1 and -2 on mu-opioid receptors in myenteric neurons and in the peristaltic reflex in rat small intestine.

@article{Storr2002EffectsOE,
  title={Effects of endomorphin-1 and -2 on mu-opioid receptors in myenteric neurons and in the peristaltic reflex in rat small intestine.},
  author={Martin Alexander Storr and Andreas Hahn and Evelyn Gaffal and Dieter Saur and H D Allescher},
  journal={Clinical and experimental pharmacology & physiology},
  year={2002},
  volume={29 5-6},
  pages={428-34}
}
1. The aim of the present investigations was to characterize the effect of endomorphins on the function of rat small intestine smooth muscle and on the electrically induced ascending and descending reflex pathway of rat small intestine in vitro. 2. Endomorphin-1 and -2 left the basal tonus and the pharmacologically stimulated smooth muscle unchanged. In contrast, electrically induced twitch contractions were significantly reduced by endomorphin-1 and -2 and this reduction was reversed by the mu… CONTINUE READING

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