Effects of enamel matrix genes on dental caries are moderated by fluoride exposures

@article{Shaffer2014EffectsOE,
  title={Effects of enamel matrix genes on dental caries are moderated by fluoride exposures},
  author={John R. Shaffer and Jenna C Carlson and Brooklyn O. C. Stanley and Eleanor Feingold and Margaret Cooper and Michael M. Vanyukov and Brion S. Maher and Rebecca L. Slayton and Marcia C. Willing and Steven E. Reis and Daniel W McNeil and Richard J Crout and Robert J. Weyant and Steven M. Levy and Alexandre R. Vieira and Mary L. Marazita},
  journal={Human Genetics},
  year={2014},
  volume={134},
  pages={159-167}
}
  • John R. Shaffer, Jenna C Carlson, +13 authors Mary L. Marazita
  • Published in Human Genetics 2014
  • Medicine, Biology
  • Dental caries (tooth decay) is the most common chronic disease, worldwide, affecting most children and adults. Though dental caries is highly heritable, few caries-related genes have been discovered. We investigated whether 18 genetic variants in the group of non-amelogenin enamel matrix genes (AMBN, ENAM, TUFT1, and TFIP11) were associated with dental caries experience in 13 age- and race-stratified samples from six parent studies (N = 3,600). Linear regression was used to model genetic… CONTINUE READING

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