Effects of emodin and baicalein on rats with severe acute pancreatitis.

  title={Effects of emodin and baicalein on rats with severe acute pancreatitis.},
  author={Xiping Zhang and Zhong-fang Li and Xiao-Gong Liu and Yong-tao Wu and Jun-Xian Wang and Kang-Min Wang and Yi-feng Zhou},
  journal={World journal of gastroenterology},
  volume={11 14},
AIM To investigate the therapeutic effects of emodin in combination with baicalein on severe acute pancreatitis (SAP) rats and to explore the mechanism of SAP. METHODS A total of 112 SAP rats induced by retrograde injection of 5% sodium taurocholate into the biliary-pancreatic duct, randomly assigned to a untreated group and three treated groups emodin group, combined emodin and baicalein group, and sandostatin group. Meanwhile, another 28 other rats were selected as sham operation (SO) group… CONTINUE READING