Effects of eltanolone on myocardial performance and coronary flow in intact and catecholamine-depleted isolated rabbit hearts.

@article{Mouren1996EffectsOE,
  title={Effects of eltanolone on myocardial performance and coronary flow in intact and catecholamine-depleted isolated rabbit hearts.},
  author={St{\'e}phane Mouren and L Abdenour and Rachid Souktani and Pierre Coriat},
  journal={Anesthesiology},
  year={1996},
  volume={85 6},
  pages={1378-85}
}
BACKGROUND Experimental studies suggest that the new short-acting intravenous anesthetic agent eltanolone does not markedly alter hemodynamics or cardiac function. However, because its intrinsic effects on myocardial performance and coronary blood flow are not yet known, they were examined in isolated blood-perfused rabbit hearts. METHODS Coronary blood flow, myocardial contractility, relaxation, and oxygen consumption were measured during perfusion of hearts with 0.1 to 10 micrograms/ml… CONTINUE READING