• Corpus ID: 1138258

Effects of electropermeabilization and gene electrotransfert on the lateral mobility of a GPi anchored protein

  title={Effects of electropermeabilization and gene electrotransfert on the lateral mobility of a GPi anchored protein},
  author={Jean-Michel Escoffre and M. Hubert and Justin Teissi'e and Marie-Pierre Rols and Cyril Favard},
  journal={arXiv: Biomolecules},
Electropermeabilization is a method by which molecules can be introduced in living cells through the plasma membrane. Here, we show that electropermeabilization affects the lateral mobility of Rae-1, a GPi anchored protein. Our results shows that 10 to 20 % of the membrane surface is occupied by defaults or pores. Gene electrotransfert also affects the lateral mobility of Rae-1. Furthermore, we clearly show that once inserted into the plasma membrane, DNA totaly excludes Rae-1, indicating that… 

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