Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.

@article{Schuldiner2000EffectsOE,
  title={Effects of eight growth factors on the differentiation of cells derived from human embryonic stem cells.},
  author={Maya Schuldiner and Ofra Yanuka and Joseph Itskovitz-Eldor and Douglas A. Melton and Nissim Benvenisty},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={2000},
  volume={97 21},
  pages={11307-12}
}
Human embryonic stem (ES) cells are pluripotent cells derived from the inner cell mass of in vitro fertilized human blastocysts. We examined the potential of eight growth factors [basic fibroblast growth factor (bFGF), transforming growth factor beta1 (TGF-beta1), activin-A, bone morphogenic protein 4 (BMP-4), hepatocyte growth factor (HGF), epidermal growth factor (EGF), beta nerve growth factor (betaNGF), and retinoic acid] to direct the differentiation of human ES-derived cells in vitro. We… CONTINUE READING
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