Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes

@article{LorenteCebrin2006EffectsOE,
  title={Effects of eicosapentaenoic acid (EPA) on adiponectin gene expression and secretion in primary cultured rat adipocytes},
  author={Silvia Lorente-Cebri{\'a}n and Patricia P{\'e}rez-Matute and J Alfredo Mart{\'i}nez and Amelia Marti and Mar{\'i}a J Moreno-Aliaga},
  journal={Journal of Physiology and Biochemistry},
  year={2006},
  volume={62},
  pages={61-69}
}
Adiponectin, a hormone produced by adipocytes, is involved in glucose metabolism and insulin sensitivity. The production of this adipokine is impaired in obesity and insulin resistance. Eicosapentaenoic acid (EPA) is a dietary n-3 polyunsaturated fatty acid that improves insulin sensitivity in several models of obesity and diabetes, which has been suggested to be related to adiponectin induction. An increase in adiponectin production has been also associated with an up-regulation of the… CONTINUE READING