Effects of efonidipine, an L- and T-type calcium channel blocker, on the renin-angiotensin-aldosterone system in chronic hemodialysis patients.

@article{Nakano2010EffectsOE,
  title={Effects of efonidipine, an L- and T-type calcium channel blocker, on the renin-angiotensin-aldosterone system in chronic hemodialysis patients.},
  author={Nobuyuki Nakano and Toshihiko Ishimitsu and Toshiaki Takahashi and Hideki Inada and Atsushi Okamura and Shuichi Ohba and Hiroaki Matsuoka},
  journal={International heart journal},
  year={2010},
  volume={51 3},
  pages={188-92}
}
Components of the renin-angiotensin-aldosterone system such as angiotensin II and aldosterone are believed to contribute to the development and progression of cardiovascular tissue and organ injuries. We compared the effects of two calcium channel blockers, efonidipine and amlodipine, on the renin-angiotensin-aldosterone system in patients with end-stage renal diseases on maintenance hemodialysis. Twenty hypertensive patients on chronic hemodialysis were given efonidipine 20-60 mg twice daily… CONTINUE READING

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