Effects of early postnatal allopregnanolone administration on elevated plus maze anxiety scores in adult male Wistar rats.


BACKGROUND/AIMS Recent findings suggest that neurosteroids are involved in brain development. The present study focused on the long-term effects of developmentally altered allopregnanolone (AlloP) levels on anxiety-like behavior in adulthood. METHOD We administered AlloP (10 mg/kg) to rat pups once a day from the 5th to the 9th day after birth. A dose… (More)
DOI: 10.1159/000328161


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