Effects of early life adverse experiences on the brain: implications from maternal separation models in rodents

@inproceedings{Nishi2014EffectsOE,
  title={Effects of early life adverse experiences on the brain: implications from maternal separation models in rodents},
  author={Mayumi Nishi and Noriko Horii-Hayashi and Takayo Sasagawa},
  booktitle={Front. Neurosci.},
  year={2014}
}
During postnatal development, adverse early life experiences affect the formation of neuronal networks and exert long-lasting effects on neural function. Many studies have shown that daily repeated maternal separation (MS), an animal model of early life stress, can regulate the hypothalamic-pituitary-adrenal axis (HPA axis) and affect subsequent brain function and behavior during adulthood. However, the molecular basis of the long-lasting effects of early life stress on brain function has not… CONTINUE READING
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