Effects of early angiotensin-converting enzyme inhibition on cardiac gene expression after acute myocardial infarction.

@article{Jin2001EffectsOE,
  title={Effects of early angiotensin-converting enzyme inhibition on cardiac gene expression after acute myocardial infarction.},
  author={Hongkui Jin and Renhui Yang and Tarif A Awad and Francis Wang and Wei Li and Simon D. P. Williams and Annie K. Ogasawara and Brian Shimada and P. Mickey Williams and Gianfranco de Feo and Nicholas F Paoni},
  journal={Circulation},
  year={2001},
  volume={103 5},
  pages={736-42}
}
BACKGROUND ACE inhibition after myocardial infarction (MI) has been shown to have beneficial effects on cardiac anatomy and function. The purpose of this study was to examine the effects of ACE inhibition on cardiac gene expression after MI. METHODS AND RESULTS Rats were randomized to receive captopril or no treatment 1 day after MI. Eight weeks later, cardiac function and hemodynamics were measured by use of indwelling catheters and perivascular flow probes. Myocardial gene expression was… CONTINUE READING
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