Effects of early and late intervention with epoetin alpha on left ventricular mass among patients with chronic kidney disease (stage 3 or 4): results of a randomized clinical trial.

@article{Roger2004EffectsOE,
  title={Effects of early and late intervention with epoetin alpha on left ventricular mass among patients with chronic kidney disease (stage 3 or 4): results of a randomized clinical trial.},
  author={Simon D. Roger and Lawrence P. McMahon and A. Kathleen Clarkson and Alex Disney and David L. Harris and Carmel M. Hawley and Helen Jean Healy and Peter M. Kerr and Kelvin Lynn and Alan Parnham and Roess Pascoe and David Voss and Robert S. Walker and Adeera Levin},
  journal={Journal of the American Society of Nephrology : JASN},
  year={2004},
  volume={15 1},
  pages={
          148-56
        }
}
It is not known whether prevention of anemia among patients with chronic kidney disease would affect the development or progression of left ventricular (LV) hypertrophy. A randomized controlled trial was performed with 155 patients with chronic kidney disease (creatinine clearance, 15 to 50 ml/min), with entry hemoglobin concentrations ([Hb]) of 110 to 120 g/L (female patients) or 110 to 130 g/L (male patients). Patients were monitored for 2 yr or until they required dialysis; the patients were… CONTINUE READING

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