Effects of eNOS polymorphisms on nitric oxide formation in healthy pregnancy and in pre-eclampsia.

@article{Sandrim2010EffectsOE,
  title={Effects of eNOS polymorphisms on nitric oxide formation in healthy pregnancy and in pre-eclampsia.},
  author={Val{\'e}ria Cristina Sandrim and Ana Carolina Taveiros Palei and Jonas Tadeu Cau Sert{\'o}rio and Ricardo Carvalho Cavalli and Geraldo Duarte and Jos{\'e} Eduardo Tanus-Santos},
  journal={Molecular human reproduction},
  year={2010},
  volume={16 7},
  pages={506-10}
}
Pre-eclampsia (PE) is associated with decreased nitric oxide (NO) formation. However, no previous study has examined whether genetic variations in the endothelial NO synthase (eNOS) affect this alteration. We hypothesized that PE decreases NO formation depending on eNOS polymorphisms. We examined how three eNOS polymorphisms [T-786C, rs2070744; Glu298Asp… CONTINUE READING