Effects of drugs on walking after spinal cord injury

  title={Effects of drugs on walking after spinal cord injury},
  author={Kathleen E. Norman and Andr{\'e} P{\'e}pin and Hugues Barbeau},
  journal={Spinal Cord},
Clonidine, a noradrenergic agonist, and cyproheptadine, a serotonergic antagonist, have each been associated with improved walking in SCI subjects. Baclofen, a GABA agonist, is frequently prescribed for spasticity but its effects on walking have not been well quantified. The objective of this study was to compare the effects of clonidine, cyproheptadine and baclofen on walking in SCI subjects with incomplete injuries. A motorized treadmill was used and harness support provided when necessary. A… CONTINUE READING


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Publications referenced by this paper.
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Does motor learning occur in the spinal cord

  • W Edgerton
  • Neurol
  • 1997

Pharmacology of locomotion in chronic spinal cats

  • S Rossignol, C Chau, H. Barbeau
  • Alpha and Gamma Motor Systems. New York: Plenum…
  • 1996

The e€ects of intrathecal clonidine on spinal re ̄exes and on locomotion in incomplete paraplegic subjects

  • O Re my-Neris
  • Abstracts from 2nd Meeting of European…
  • 1996

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