Effects of drugs affecting the noradrenergic system on convulsions in the quaking mouse

@article{Chermat2004EffectsOD,
  title={Effects of drugs affecting the noradrenergic system on convulsions in the quaking mouse},
  author={Raymond Chermat and Liliane Doar{\'e} and François Lachapelle and Pierre Simon},
  journal={Naunyn-Schmiedeberg's Archives of Pharmacology},
  year={2004},
  volume={318},
  pages={94-99}
}
SummaryHandling-induced convulsions in the quaking mouse can be blocked by: phenobarbital, pentobarbital or phenytoin; postsynaptic alpha-adrenoceptor agonists (noradrenaline, phenylephrine, CRL 40028); presynaptic alpha-adrenoceptor blockers (yohimbine, mianserine); catecholamine liberating agent (amphetamine); noradrenaline reuptake inhibitors (cocaine, imipramine, desipramine).Moreover, the protective effect of yohimbine was antagonized by clonidine, prazosin or alpha-methylparatyrosine, and… 
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