Effects of double-strand break repair proteins on vertebrate telomere structure

@article{Wei2002EffectsOD,
  title={Effects of double-strand break repair proteins on vertebrate telomere structure},
  author={Chao Wei and Rose Skopp and Minoru Takata and Shunichi Takeda and Carolyn M. Price},
  journal={Nucleic acids research},
  year={2002},
  volume={30 13},
  pages={
          2862-70
        }
}
Although telomeres are not recognized as double-strand breaks (DSBs), some DSB repair proteins are present at telomeres and are required for telomere maintenance. To learn more about the telomeric function of proteins from the homologous recombination (HR) and non-homologous end joining pathways (NHEJ), we have screened a panel of chicken DT40 knockout cell lines for changes in telomere structure. In contrast to what has been observed in Ku-deficient mice, we found that Ku70 disruption did not… CONTINUE READING
Highly Cited
This paper has 20 citations. REVIEW CITATIONS

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations