Effects of dopamine of cerebral circulation and oxygen metabolism in endotoxic shock: an experimental study in dogs.

Abstract

Experimental endotoxic shock in normocapnic dogs decreases cerebral blood flow (CBF) and increases cerebral metabolic rate of oxygen (CMRO2). In 6 animals, an iv injection of 1.0-1.5 mg/kg of Escherichia coli endotoxin was followed by iv infusion of dopamine HCI at a rate of 3-24 Micrograms/kg . min. Doses of only 5 micrograms/kg . min maximally increased… (More)

Topics

  • Presentations referencing similar topics