Effects of dopamine and aminophylline on contrast-induced acute renal failure after coronary angioplasty in patients with preexisting renal insufficiency.

@article{Abizaid1999EffectsOD,
  title={Effects of dopamine and aminophylline on contrast-induced acute renal failure after coronary angioplasty in patients with preexisting renal insufficiency.},
  author={Andrea Claudia Le{\~a}o de Souza Abizaid and Chester Clark and Gary S. Mintz and S{\'a}ndor D{\'o}sa and Jeffrey J. Popma and Augusto D. Pichard and Lowell F Satler and Mark Harvey and Kenneth M. Kent and Martin B. Leon},
  journal={The American journal of cardiology},
  year={1999},
  volume={83 2},
  pages={260-3, A5}
}
In phase 1 of this study, 60 patients undergoing coronary angioplasty were randomized to receive saline, dopamine, or aminophylline; the overall incidence of contrast-induced renal failure was 38%, without difference among the 3 groups. In phase 2 of this study, 72 patients with established contrast-induced renal failure were randomized to receive saline or dopamine; dopamine had a deleterious effect on the severity of renal failure, prolonging the course. 

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