Effects of donor cell type and genotype on the efficiency of mouse somatic cell cloning.

@article{Inoue2003EffectsOD,
  title={Effects of donor cell type and genotype on the efficiency of mouse somatic cell cloning.},
  author={Kimiko Inoue and Narumi Ogonuki and Keiji Mochida and Yoshie Yamamoto and Kaoru Takano and Takashi Kohda and F. Ishino and Atsuo Ogura},
  journal={Biology of reproduction},
  year={2003},
  volume={69 4},
  pages={1394-400}
}
Although it is widely assumed that the cell type and genotype of the donor cell affect the efficiency of somatic cell cloning, little systematic analysis has been done to verify this assumption. The present study was undertaken to examine whether donor cell type, donor genotype, or a combination thereof increased the efficiency of mouse cloning. Initially we assessed the developmental ability of embryos that were cloned from cumulus or immature Sertoli cells with six different genotypes (i.e… CONTINUE READING

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