Effects of divalent cations on chloride movement across amphibian skin

@article{Nagel1988EffectsOD,
  title={Effects of divalent cations on chloride movement across amphibian skin},
  author={Wolfram Nagel and Yu. V. Natochin and James Stanley Crabbe},
  journal={Pfl{\"u}gers Archiv},
  year={1988},
  volume={411},
  pages={540-545}
}
Effects of the divalent heavy metal ions Cd2+, Co2+, Cu2+, Mn2+, Ni2+, and Zn2+ on pathways for sodium and chloride were assessed on isolated amphibian skin (Rana temporaria andesculenta, Bufo marinus andviridis). It was observed that these agents, in addition to the previously reported stimulation of sodium transport, inhibit chloride-related tissue conductance (gCl) in frog skin with spontaneously highgCl when added to the external incubation medium. Serosal application was ineffective. Half… CONTINUE READING
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