Effects of dithiothreitol on the isolated rabbit mesenteric artery

Abstract

Rabbit mesenteric artery strips exposed to 10−3 M dithiothreitol (DTT) were contracted with a series of concentrations of histamine and 2-pyridylethylamine (PEA). DTT exposure increased the sensitivity to histamine 100-fold but increased the sensitivity to PEA only 4-fold. DTT did not reduce dimaprit-induced relaxations, but reduced histamine-induced… (More)
DOI: 10.1007/BF01965924

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