Effects of dissolved oxygen on the morphology of an arachidonic acid production by Mortierella alpina 1S-4.

@article{Higashiyama1999EffectsOD,
  title={Effects of dissolved oxygen on the morphology of an arachidonic acid production by Mortierella alpina 1S-4.},
  author={Kenichi Higashiyama and Kohji Murakami and Hiroji Tsujimura and Norio Matsumoto and Seizo Fujikawa},
  journal={Biotechnology and bioengineering},
  year={1999},
  volume={63 4},
  pages={442-8}
}
Arachidonic acid (AA) production by Mortierella alpina 1S-4 was investigated using a 50-L fermentor. In order to optimize the dissolved oxygen (DO) concentration and to investigate the effect of DO on morphology, cultivation was carried out under constant DO at various levels in the range of 3-50 ppm. To maintain a DO concentration above 7 ppm, two methods, i.e., the oxygen-enrichment (OE) method (experimental range, 25-90% oxygen gas supplied) and the pressurization (PR) method (experimental… CONTINUE READING

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