Effects of disease activity on anti-Saccharomyces cerevisiae antibodies: implications for diagnosis and follow-up of children with Crohn's disease.

@article{Canani2004EffectsOD,
  title={Effects of disease activity on anti-Saccharomyces cerevisiae antibodies: implications for diagnosis and follow-up of children with Crohn's disease.},
  author={Roberto Berni Canani and Maria Teresa Romano and Luigi Giovanni Greco and Gianluca Terrin and Concetta Sferlazzas and Arrigo Vittorio Barabino and Massimo Fontana and Paola Roggero and Graziella Guariso and GianLuigi De Angelis and Simona Fecarotta and Gaetano Polito and Salvatore Cucchiara},
  journal={Inflammatory bowel diseases},
  year={2004},
  volume={10 3},
  pages={
          234-9
        }
}
BACKGROUND To determine diagnostic accuracy of anti-Saccharomyces cerevisiae antibodies (ASCA) in identifying children with inflammatory bowel disease (IBD) and to differentiate Crohn's disease (CD) from other IBD forms; and to determine the effect of medical or surgical treatment and of disease location and activity on ASCA titers. METHODS Serum samples were obtained from 196 IBD children and 142 controls. ASCA IgA and IgG titers were measured by ELISA. Measurements were repeated during the… CONTINUE READING
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