Effects of dihydropyridine-type Ca2+ antagonists on the renal arterial tree in spontaneously hypertensive rats.

@article{Sabbatini2002EffectsOD,
  title={Effects of dihydropyridine-type Ca2+ antagonists on the renal arterial tree in spontaneously hypertensive rats.},
  author={Maurizio Sabbatini and Amedeo Leonardi and Rodolfo Testa and Daniele Tomassoni and Lucia Vitaioli and Francesco Amenta},
  journal={Journal of cardiovascular pharmacology},
  year={2002},
  volume={39 1},
  pages={39-48}
}
The effects of hypertension and of treatment with dihydropyridine-type Ca2+ antagonists and the vasodilator hydralazine on renal arterial tree were investigated in spontaneously hypertensive rats (SHR) with quantitative microanatomical techniques. Pharmacological treatment decreased to a similar extent systolic blood pressure values in SHR. Increased thickness of the tunica media of intrarenal arteries accompanied and luminal narrowing were observed in control SHR. Lercanidipine, manidipine… CONTINUE READING

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