Effects of different natriuretic peptides on nitric oxide synthesis in macrophages.

@article{Kiemer1997EffectsOD,
  title={Effects of different natriuretic peptides on nitric oxide synthesis in macrophages.},
  author={Alexandra K Kiemer and Angelika M. Vollmar},
  journal={Endocrinology},
  year={1997},
  volume={138 10},
  pages={
          4282-90
        }
}
Atrial natriuretic peptide (ANP) has previously been suggested to inhibit the production of NO in LPS-activated primary macrophages. The aim of the present study was 1) to examine whether ANP elicits this effect also on macrophage cell lines (RAW 264.7, J774), 2) to elucidate whether ANP is the only natriuretic peptide (NP) inhibiting NO synthesis, 3) to look for the expression of natriuretic peptide receptors (NPR) on macrophages, 4) to consequently determine the type of receptor mediating the… CONTINUE READING

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