Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema

@inproceedings{Antunes2014EffectsOD,
  title={Effects of different mesenchymal stromal cell sources and delivery routes in experimental emphysema},
  author={Mariana Alves Antunes and Soraia Carvalho Abreu and Fernanda Ferreira Cruz and Ana Clara Bortoluzzi Teixeira and Miqu{\'e}ias Lopes-Pacheco and Elga Bandeira and Priscilla Christina Olsen and Bruno Lourenço Diaz and Christina Maeda Takyia and Isalira Prg Freitas and Nazareth de Novaes Rocha and Vera L{\'u}cia Capelozzi and D{\'e}bora Gonçalves Xisto and Daniel Jay Weiss and Marcelo Marcos Morales and Patricia Rieken Mac{\^e}do Rocco},
  booktitle={Respiratory research},
  year={2014}
}
We sought to assess whether the effects of mesenchymal stromal cells (MSC) on lung inflammation and remodeling in experimental emphysema would differ according to MSC source and administration route. Emphysema was induced in C57BL/6 mice by intratracheal (IT) administration of porcine pancreatic elastase (0.1 UI) weekly for 1 month. After the last elastase instillation, saline or MSCs (1-105), isolated from either mouse bone marrow (BM), adipose tissue (AD) or lung tissue (L), were administered… CONTINUE READING
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