Effects of different meal compositions and fasted state on the oral bioavailability of etravirine.

Abstract

STUDY OBJECTIVE To determine the effects of various meal compositions and the fasted state on the pharmacokinetics of etravirine, a nonnucleoside reverse transcriptase inhibitor. DESIGN Phase I, open-label, randomized, repeated single-dose, three-period crossover trial. SETTING Clinical pharmacology unit. PARTICIPANTS Two parallel panels of 12 human… (More)
DOI: 10.1592/phco.28.10.1215

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