Corpus ID: 35940826

Effects of different dose regimens of magnesium on pharmacodynamics and anesthetic requirements of balanced general anesthesia.

@article{Khafagy2007EffectsOD,
  title={Effects of different dose regimens of magnesium on pharmacodynamics and anesthetic requirements of balanced general anesthesia.},
  author={H. Khafagy and Emad S. Osman and A. Naguib},
  journal={Journal of the Egyptian Society of Parasitology},
  year={2007},
  volume={37 2},
  pages={
          469-82
        }
}
The present double- blind, randomized, placebo-controlled study was designed to assess the effect of two different dose regimens of magnesium sulphate (MgSO4) administration on intraoperative propofol and vecuronium requirements and postoperative fentanyl consumption in patients undergoing hernioraphy. Sixty patients were allocated to three equal groups; two magnesium groups and control group. Magnesium groups received 50 mg kg(-1) of magnesium preoperatively followed by intravenous infusion of… Expand
Influence of the perioperative administration of magnesium sulfate on the total dose of anesthetics during general anesthesia. A systematic review and meta-analysis.
TLDR
It is concluded that perioperative magnesium sulfate acts as a coadjuvant drug capable of reducing anesthetic requirements. Expand
Interaction between magnesium sulfate and neuromuscular blockers during the perioperative period. A systematic review and meta-analysis.
TLDR
The administration of magnesium sulfate during the perioperative period alters neuromuscular blockade pharmacodynamics causing a shortening of the onset time, prolongs the clinical duration, and improves the recovery time of these drugs. Expand
Magnesium Mama and the Mad Dad
This case discusses pharmacodynamic drug–drug interactions between magnesium sulfate and intravenous anesthetics and between magnesium sulfate and vecuronium. Additional information regarding the useExpand