Effects of different cyclodextrins on the morphology, loading and release properties of poly (DL-lactide-co-glycolide)-microparticles containing the hypnotic agent etizolam

@article{Lopedota2007EffectsOD,
  title={Effects of different cyclodextrins on the morphology, loading and release properties of poly (DL-lactide-co-glycolide)-microparticles containing the hypnotic agent etizolam},
  author={A. Lopedota and A. Cutrignelli and A. Trapani and G. Boghetich and N. Denora and V. Laquintana and G. Trapani and G. Liso},
  journal={Journal of Microencapsulation},
  year={2007},
  volume={24},
  pages={214 - 224}
}
  • A. Lopedota, A. Cutrignelli, +5 authors G. Liso
  • Published 2007
  • Materials Science, Medicine
  • Journal of Microencapsulation
  • The aim of this study was to gain insight into the feasibility of using microparticles (MPs) constituted by the biodegradable poly (DL-lactide-co-glycolide) (PLGA) and a number of cyclodextrins (CDs) as an orally sustained delivery system of the hypnotic agent etizolam (ETZ). A further aim of the work was to investigate the effects of different CDs on the morphology, loading, and release properties of the MPs prepared. For these purposes, ETZ alone, and ETZ/CD-PLGA loaded MPs were prepared by… CONTINUE READING
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    References

    SHOWING 1-10 OF 17 REFERENCES
    Encapsulation and release of the hypnotic agent zolpidem from biodegradable polymer microparticles containing hydroxypropyl-beta-cyclodextrin.
    • 26
    Poly(lactide-co-glycolide) microspheres for the controlled release of oligonucleotide/polyethylenimine complexes.
    • 60
    Cyclodextrins and carrier systems.
    • 144
    Effects of salt addition on the microencapsulation of proteins using W/O/W double emulsion technique.
    • 112
    Mechanisms by which cyclodextrins modify drug release from polymeric drug delivery systems.
    • 245
    Improvement of the encapsulation efficiency of oligonucleotide-containing biodegradable microspheres.
    • 122
    Osmotic Properties of Sulfobutylether and Hydroxypropyl Cyclodextrins
    • 33
    In vitro characterization of methotrexate loaded poly(lactic-co-glycolic) acid microspheres and antitumor efficacy in Sarcoma-180 mice bearing tumor.
    • 26