Effects of different ACE inhibitor combinations on albuminuria: results of the GUARD study.

@article{Bakris2008EffectsOD,
  title={Effects of different ACE inhibitor combinations on albuminuria: results of the GUARD study.},
  author={George L Bakris and Robert Daniel Toto and Peter A. McCullough and Ricardo Rocha and Das Purkayastha and Pamela H Davis},
  journal={Kidney international},
  year={2008},
  volume={73 11},
  pages={1303-9}
}
Clinical practice guidelines recommend blockers of the renin-angiotensin system alone or in combination with other agents to reduce blood pressure and albuminuria in patients with type 2 diabetes. Dihydropyridine calcium channel blockers, however, may lower blood pressure but not albuminuria in these patients. Here we tested the hypothesis that combining an ACE inhibitor with either a thiazide diuretic or a calcium channel blocker will cause similar reductions in blood pressure and albuminuria… CONTINUE READING