Effects of diethylstilbestrol exposure during gestation on both maternal and offspring behavior

@inproceedings{Tomihara2015EffectsOD,
  title={Effects of diethylstilbestrol exposure during gestation on both maternal and offspring behavior},
  author={Kazuya Tomihara and Takahiro Zoshiki and Sayaka Y. Kukita and Kanako Nakamura and Ayuko Isogawa and Sawako Ishibashi and Ayumi Tanaka and Ayaka S. Kuraoka and Saki Matsumoto},
  booktitle={Front. Neurosci.},
  year={2015}
}
Endocrine disruption during gestation impairs the physical and behavioral development of offspring. However, it is unclear whether endocrine disruption also impairs maternal behavior and in turn further contributes to the developmental and behavioral dysfunction of offspring. We orally administered the synthetic non-steroidal estrogen diethylstilbestrol (DES) to pregnant female C57BL/6J mice from gestation day 11-17 and then investigated the maternal behavior of mothers. In addition, we… CONTINUE READING