Effects of dietary tryptophan variations on extracellular serotonin in the dorsal hippocampus of rats

@article{Stelt2004EffectsOD,
  title={Effects of dietary tryptophan variations on extracellular serotonin in the dorsal hippocampus of rats},
  author={Hiske M. van der Stelt and Laus M Broersen and Berend Olivier and Herman G. M. Westenberg},
  journal={Psychopharmacology},
  year={2004},
  volume={172},
  pages={137-144}
}
There is evidence to suggest that the efficacy of selective serotonin reuptake inhibitors (SSRIs) in depression is dependent on the availability of serotonin (5-HT) in the brain. Moreover, there is circumstantial evidence suggesting that plasma tryptophan (TRP) levels can predict response to SSRIs. These findings suggest that dietary TRP variations may… CONTINUE READING