Effects of dietary selenium on UVB-induced skin carcinogenesis and epidermal antioxidant status.

@article{Pence1994EffectsOD,
  title={Effects of dietary selenium on UVB-induced skin carcinogenesis and epidermal antioxidant status.},
  author={Barbara C. Pence and Eugene P Delver and Dale M. Dunn},
  journal={The Journal of investigative dermatology},
  year={1994},
  volume={102 5},
  pages={759-61}
}
Low plasma selenium levels have been linked to increased risk of non-melanoma skin cancer in humans. The present study examined the relationship between selenium level in the diet and development of skin tumors induced by ultraviolet radiation in female Skh:HR-1 hairless mice. Animals were maintained on a torula yeast-based diet containing either 0, 0.1, or 0.5 mg/kg selenium as Na2SeO3. Ultraviolet light at a dose of 90 mJ/cm2, three times weekly for 20 weeks, resulted in skin tumors in all… CONTINUE READING
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