Effects of dietary menhaden oil on DNA adducts of the food mutagen 2-amino-3-methylimidazo[4,5-f]quinoline (IQ) in Fischer-344 rats.

Abstract

2-Amino-3-methylimidazo[4,5-f]quinoline (IQ) is a food mutagen which has been found to be carcinogenic in the Fischer-344 rat. We have assessed the effects of a diet containing menhaden oil on IQ-DNA adduct formation in several organs of the male Fischer-344 rat. Young adult, male Fischer-344 rats were maintained on either a) an AIN-76A diet, containing 5… (More)

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