Effects of dietary fatty acid composition on the regulation of carnitine palmitoyltransferase (CPT) I in rainbow trout (Oncorhynchus mykiss).

@article{Morash2009EffectsOD,
  title={Effects of dietary fatty acid composition on the regulation of carnitine palmitoyltransferase (CPT) I in rainbow trout (Oncorhynchus mykiss).},
  author={Andrea J. Morash and Dominique P. Bureau and Grant B. McClelland},
  journal={Comparative biochemistry and physiology. Part B, Biochemistry \& molecular biology},
  year={2009},
  volume={152 1},
  pages={
          85-93
        }
}

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References

SHOWING 1-10 OF 50 REFERENCES

The effect of dietary lipid manipulation on hepatic mitochondrial phospholipid fatty acid composition and carnitine palmitoyltransferase I activity.

It is proposed that the effects of dietary lipid manipulation upon CTP I activity and sensitivity to inhibition by malonyl CoA are due to alterations in the fatty acid composition of the phospholipids in the mitochondrial membrane where CPT I resides.

Dietary fatty acid composition changes mitochondrial phospholipids and oxidative capacities in rainbow trout red muscle

Neither general characteristics of membrane FA, nor levels of abundant unsaturated FA such as DHA or 18:1(n-9 + n-7), were systematically correlated with mitochondrial capacities even though they differed considerably between trout fed the different diets.

The Effect of Dietary Lipid and Long‐chain n‐3 PUFA Levels on Growth, Energy Utilization, Carcass Quality, and Immune Function of Rainbow Trout, Oncorhynchus mykiss

The study suggests that highly saturated fats, such as beef tallow, can be used to partially replace fish oil without negative effect on digestibility and growth even at low water temperature.

Co-ordinate induction of hepatic mitochondrial and peroxisomal carnitine acyltransferase synthesis by diet and drugs.

The results of the combined studies using both diet and drugs to cause enzyme induction suggest that the synthesis of the carnitine acyltransferases (mitochondrial CPT and peroxisomal CPTs) may be co-ordinated with each other; however, the co-ordinate regulatory factors have not yet been identified.

Fatty Acids Activate Transcription of the Muscle Carnitine Palmitoyltransferase I Gene in Cardiac Myocytes via the Peroxisome Proliferator-activated Receptor α*

It is demonstrated that long-chain fatty acids regulate the transcription of a gene encoding a pivotal enzyme in the mitochondrial fatty acid uptake pathway in cardiac myocytes and define a role for PPARα in the control of myocardial lipid metabolism.

Mitochondrial function in rats is affected by modification of membrane phospholipids with dietary sardine oil.

The O2 consumption rate of rat heart mitochondria decreased as the fatty acid composition of the phospholipids changed, and the reduction of the activity of cytochrome c oxidase, which requires cardiolipin for its activity.

STRUCTURE, FUNCTION, AND DIETARY REGULATION OF Δ6, Δ5, AND Δ9 DESATURASES

Delta-6 and Δ5 desaturases are required for the synthesis of highly unsaturated fatty acids (HUFAs), which are mainly esterified into phospholipids and contribute to maintaining membrane fluidity, and may be required for cold tolerance in plants and fish.