Effects of dietary fat, NaCl, and fructose on renal sodium and water transporter abundances and systemic blood pressure.

@article{Song2004EffectsOD,
  title={Effects of dietary fat, NaCl, and fructose on renal sodium and water transporter abundances and systemic blood pressure.},
  author={Jian Song and Xin-qun Hu and Min Shi and Mark A. Knepper and Carolyn M A Ecelbarger},
  journal={American journal of physiology. Renal physiology},
  year={2004},
  volume={287 6},
  pages={F1204-12}
}
Dietary fructose, NaCl, and/or saturated fat have been correlated with mean arterial pressure (MAP) rises in sensitive strains of rats. Dysregulation of sodium and/or water reabsorption by the kidney may contribute. Using radiotelemetry and parallel semiquantitative immunoblotting, we examined the effects of various diets on MAP and the regulation of abundance of the major renal sodium and water transport proteins in male Sprague-Dawley rats. In study 1, rats ( approximately 275 g) were fed one… CONTINUE READING