Effects of dietary exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in adult female mink (Mustela vison).

@article{Hochstein1998EffectsOD,
  title={Effects of dietary exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin in adult female mink (Mustela vison).},
  author={Jason Hochstein and Steven J Bursian and Richard J. Aulerich},
  journal={Archives of environmental contamination and toxicology},
  year={1998},
  volume={35 2},
  pages={348-53}
}
Adult female mink were fed diets supplemented with 0, 0.001, 0.01, 0.1, 1, 10, or 100 ppb 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) for up to 125 days. There was a dose-dependent decrease in feed consumption and body weights indicative of the "wasting syndrome" previously reported for mink and other species exposed to chlorinated hydrocarbon compounds. Mortality reached 12.5, 62.5, and 100% by day 28 in the 1-, 10-, and 100-ppb groups, respectively, and by day 125, mortality increased to 62.5… CONTINUE READING