Effects of diet-induced hyperthreoninemia. I). Amino acid levels in the central nervous system and peripheral tissues.

@article{Castagn1993EffectsOD,
  title={Effects of diet-induced hyperthreoninemia. I). Amino acid levels in the central nervous system and peripheral tissues.},
  author={Vincent Castagn{\'e} and Denis Mo{\"e}nnoz and Patrick Finot and Jean Claude Maire},
  journal={Life sciences},
  year={1993},
  volume={53 24},
  pages={
          1803-10
        }
}
Rats were fed four levels of threonine (Thr, 0.4, 0.6, 0.8, and 5.8 g/100 g diet). After two weeks, Thr, serine (Ser), and glycine (Gly) levels were measured in plasma, liver, muscle, and central nervous system. The diet containing 5.8 g/100 g of Thr elevated Thr and Gly concentrations in plasma and nervous tissue in comparison with a standard diet. In muscle and liver, Thr concentrations were also raised but Gly levels did not change. The hepatic Thr dehydratase activity was enhanced. Diets… CONTINUE READING
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