Effects of dichloromethylene diphosphonate, ethane-1-hydroxy-1,1-diphosphonate, and rickets in rats.

@article{OHara1975EffectsOD,
  title={Effects of dichloromethylene diphosphonate, ethane-1-hydroxy-1,1-diphosphonate, and rickets in rats.},
  author={J P O'Hara and Jenifer Jowsey and Grant A Williams},
  journal={The Journal of laboratory and clinical medicine},
  year={1975},
  volume={86 5},
  pages={793-802}
}
This study compared bone remodeling, bone mineralization, and parathyroid hormone secretion in rats treated with ethane-1-hydroxy-1,1-diphosphonate (EHDP) or dichloromethylene diphosphonate (Cl2MDP). The results were compared with findings in rachitic and control rats. In addition, calcification was induced in the skin by administration of lead acetate… CONTINUE READING