Effects of diazepam on Mycobacterium bovis-induced infection in hamsters.

  title={Effects of diazepam on Mycobacterium bovis-induced infection in hamsters.},
  author={Dario A Righi and S{\^o}nia Regina A A Pinheiro and Jos{\'e} Luiz Guerra and Jo{\~a}o Palermo-Neto},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  volume={32 9},
The in utero exposure of hamsters to low doses of diazepam results in impaired host defense against Mycobacterium bovis during adulthood. Delayed developmental immunotoxicity, however, represents a specific situation that might not be general. The present experiment was undertaken to investigate the effects of diazepam on hamster resistance to M. bovis using adult animals. The effects of diazepam treatment on serum cortisol levels were also studied. Adult hamsters (N = 10 for each group) were… CONTINUE READING


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