Effects of diazepam, ethanol and Ro 15-1788 on ultrasonic vocalization, locomotor activity and body righting in the neonatal rat.

@article{Engel1987EffectsOD,
  title={Effects of diazepam, ethanol and Ro 15-1788 on ultrasonic vocalization, locomotor activity and body righting in the neonatal rat.},
  author={J{\"o}rgen A. Engel and Ernest H{\aa}rd},
  journal={Alcohol and alcoholism (Oxford, Oxfordshire). Supplement},
  year={1987},
  volume={1},
  pages={709-12}
}
It has been suggested that ethanol, besides its stimulating, sedative and ataxic effects, also exerts anxiolytic effects similarly to diazepam. In the present study we tested this hypothesis on ultrasonic distress crying in neonatal rats separated from mother and litter-mates. The results showed that both ethanol and diazepam reduced crying in a dose-dependent manner and at doses not affecting the level of motor activity. It was found that the effects of diazepam, but not that of ethanol, was… CONTINUE READING