Effects of dexmedetomidine on propofol and remifentanil infusion rates during total intravenous anesthesia for spine surgery in adolescents.

@article{Ngwenyama2008EffectsOD,
  title={Effects of dexmedetomidine on propofol and remifentanil infusion rates during total intravenous anesthesia for spine surgery in adolescents.},
  author={Nkanyezi E Ngwenyama and John Thomas Anderson and Daniel G. Hoernschemeyer and Joseph Drew Tobias},
  journal={Paediatric anaesthesia},
  year={2008},
  volume={18 12},
  pages={
          1190-5
        }
}
INTRODUCTION Total intravenous anesthesia with propofol and a synthetic opioid is a frequently chosen anesthetic technique for posterior spinal fusion. Despite its utility, adverse effects may occur with high or prolonged propofol dosing regimens including delayed awakening. The current study investigated the propofol-sparing effects of the concomitant administration of the alpha(2)-adrenergic agonist, dexmedetomidine, during spinal fusion surgery in adolescents. METHODS The surgical database… CONTINUE READING

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