Effects of dexmedetomidine on cerebral blood flow in critically ill patients with or without traumatic brain injury: a prospective controlled trial.

@article{Wang2013EffectsOD,
  title={Effects of dexmedetomidine on cerebral blood flow in critically ill patients with or without traumatic brain injury: a prospective controlled trial.},
  author={Xuemin Wang and Junhui Ji and Liang Fen and Aizhong Wang},
  journal={Brain injury},
  year={2013},
  volume={27 13-14},
  pages={1617-22}
}
STUDY OBJECTIVE To examine the effect of dexmedetomidine on CBF in critical ill patients with or without TBI. RESEARCH DESIGN Prospective controlled trial (ISRCTN57998533). METHODS Fifteen patients without TBI and 20 patients with TBI with a Glasgow Coma Scale score of 4-14 were assigned to CON or TBI groups, respectively. All patients received 1 μg kg(-1) dexmedetomidine infused over 10 minutes, followed by a 0.4 μg kg(-1)h(-1) continuous infusion for 60 minutes. Blood pressure was… CONTINUE READING
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