Effects of dexamethasone on the expression of myelin basic protein, proteolipid protein, and glial fibrillary acidic protein genes in developing rat brain.

@article{Tsuneishi1991EffectsOD,
  title={Effects of dexamethasone on the expression of myelin basic protein, proteolipid protein, and glial fibrillary acidic protein genes in developing rat brain.},
  author={Syuichi Tsuneishi and Satoshi Takada and Toshiyuki Motoike and Tamaki Ohashi and Kimihiko Sano and H Nakamura},
  journal={Brain research. Developmental brain research},
  year={1991},
  volume={61 1},
  pages={
          117-23
        }
}
Effects of dexamethasone (DEX) on the relative abundance of myelin basic protein (MBP), proteolipid protein (PLP) and glial fibrillary acidic protein (GFAP) mRNAs in the developing rat brain were examined. After DEX (1.0 mg/kg body weight) or saline was administered intraperitoneally to 3-day-old rats for 7 consecutive days, wet weight, DNA content and the relative abundance of the glia-specific mRNAs in cerebrum and cerebellum were analyzed at postnatal days (P) 10, 20 and 30. DEX decreased… CONTINUE READING

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